Event Date
Genome Center is hosting the Annual David L. Weaver Endowed Lectures in Biophysics and Computational Biology.
From Integrative Structural Biology to Cell Biology
Professor Andrej Sali
Research Collaboratory for Structural Bioinformatics Protein
Data Bank, Department of Bioengineering and Therapeutic
Sciences, Quantitative Biosciences Institute (QBI), and
Department of Pharmaceutical Chemistry, University of
California, San Francisco, San Francisco, California, USA
Professor Andrej Sali, a computational structural biologist joined the University of California, San
Francisco in 2003 as a Professor for the Department of Bioengineering and Therapeutic Sciences.
Professor Sali received his PhD in Biophysics at the University of London, and his BSc in Chemistry at
the University of Ljubljana, Slovenia. Professor Sali has a broad background in computational
structural biology, with emphasis on structural modeling and simulations: In the past, he developed
and applied methods for comparative protein structure modeling and functional annotation of
proteins as well as contributed to the understanding of the protein folding process. Presently, the
major research objective of his group is to develop, apply, and disseminate integrative models of
biomolecular structures and networks that are consistent with all available information from
experimental methods, physical theories, and statistical inference. This integrative approach
maximizes efficiency, accuracy, resolution, completeness, and applicability of modeling. In
collaboration with experimentalists, they are applying their methods to specific systems, resulting in,
for example, the first complete structures of the eukaryotic ribosome, nuclear pore complex, and
the 26S proteasome. His group is also contributing to the impact of integrative structure modeling by
building a new module of the worldwide PDB for depositing, validating, and disseminating
integrative structures as widely as possible. Recently, his group invented an instance of integrative
modeling that aims to combine different types of models with each other, in an effort to contribute
to the mapping of the cell.
Wednesday, April 2, 2025
3:00pm-4:00pm
Genome and Biomedical Sciences Facility, Auditorium
Reception to follow
Join remotely via Zoom: https://ucdavis.zoom.us/j/99041566810 (Meeting ID: 990 4156 6810)
The lecture is free and open to the community. The series honors the memory of David L. Weaver, a distinguished biophysicist and professor at Tufts University for whom the endowment was established in 2006.
For information on this or previous lectures, please visit our David L. Weaver Endowed Lectures in Biophysics and Computational Biology webpage.
Learn more about the event here.