Michael Cianfrocco, Assistant Professor, University of Michigan, presents "Pump the Brakes: Mechanisms to Turn Off Kinesin Motors".

Michael Cianfrocco is a faculty member at the University of Michigan, where he is an Assistant Professor in the Departments of Biological Chemistry and Biophysics and a Research Assistant Professor at the Life Sciences Institute. Michael has used cryo-electron microscopy for the past 17 years since training as a graduate student with Eva Nogales and then as a post-doctoral fellow with Sam Reck-Peterson and Andres Leschziner. Since starting his group in 2017, Michael has utilized reconstitution biochemistry, single-molecule imaging, and cryo-EM to understand how motor proteins are regulated and how they attach to cargo. In parallel, Michael has continued to push on methods and cyberinfrastructure developments in cryo-EM, serving as the director of the COSMIC2 platform for structural biology research and education (cosmic2.sdsc.edu).

Host: Richard McKenney (rjmckenney@ucdavis.edu)