In a new study published in Science Advances on September 10, a team of UC Davis researchers tracked the movement of fluorescent particles inside the cells of microscopic worms, providing unprecedented insights into cellular crowding in a multicellular animal. They found that the cytoplasm inside the worms was significantly more crowded and compartmentalized than in single-celled yeast or mammalian tissue culture cells, which are more commonly used to gauge internal cellular dynamics.
The mind of a fruit fly encompasses 125,000 nerve cells, squeezed into the space of a poppy seed. At first glance, the fly brain looks nothing like a human brain. But many of the underlying neural circuits are surprisingly similar.
Fumika Hamada, a professor of neurobiology, physiology, and behavior, is using fruit flies to study a critical but oft-overlooked brain function: the regulation of our body temperature in a consistent daily rhythm.
Human eyes are complex and irreparable, yet they are structurally like those of the freshwater apple snail, which can completely regenerate its eyes. Alice Accorsi, assistant professor of molecular and cellular biology at the University of California, Davis, studies how these snails regrow their eyes — with the goal of eventually helping to restore vision in people with eye injuries.
What makes the human brain distinctive? A new study published July 21 in Cell identifies two genes linked to human brain features and provides a road map to discover many more. The research could lead to insights into the functioning and evolution of the human brain, as well as the roots of language disorders and autism.
Where do you go when you’re a fish and you need a skincare treatment? Coral reefs contain natural “beauty salons,” lively social hubs of activity where fish “clients” swim up and wait to be serviced by smaller fish cleaners. The little cleaners dart under and around their much bigger clients — even entering their mouths — cleaning their scales of bacteria and parasites like a team of car washers servicing a Buick. Sometimes cleaners even rub against their clients, providing a soothing massage.
Neil Hunter, a professor in the Department of Microbiology and Molecular Genetics and an Investigator with the Howard Hughes Medical Institute, has been elected as a Fellow of The Royal Society in London.
This prestigious appointment, announced May 20, was offered to only 70 scientists across the world.
“I’m thrilled and surprised,” said Hunter. “The acknowledgment means a great deal to me, because it’s an election by some of the best scientists in the world.”
When drug breakthroughs happen, the medical community rejoices. But some people can be left behind. Case in point: Rapamycin. Now a UC Davis professor is investigating how to bring back the benefits of a revolutionary drug to the people who were there from the beginning.
The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea. But sometimes it triggers severe, even fatal disease by chewing ulcers in the colon, liquefying parts of the liver and invading the brain and lungs.
A single set of genetic instructions produces thousands of structures in our bodies – from nerve cells that branch like gnarled oak trees, to osteoblast cells that sculpt minerals into bone. It begins with the delicate formation of sperm and eggs – which ignite the miraculous unfurling of an entire body from a single cell.
For this to happen, DNA must be precisely folded and coiled into the sperm and egg cells – creating a structure that coordinates thousands of genes, says Satoshi Namekawa, a professor of microbiology and molecular genetics.
