Extramurally Funded Research

A Baby Bird’s Wishlist: Mild Weather, Attentive Parents, Not Being the Smallest Sibling

Experiences in the first days and weeks of life can have a profound impact on humans — and birds. A new study led by Sage Madden, a graduate student working with Gail Patricelli, a professor of evolution and ecology, shows how weather conditions and family dynamics affect the growth of barn swallow (Hirundo rustica erythrogaster) chicks. 

Children with Rare, Debilitating Brain Diseases Suffer from Mutations in a Little-Known Protein Complex

Thousands of times per year, a family’s moment of joy turns to unexpected grief. A seemingly healthy infant stops smiling or making eye contact. Their limbs grow weak. The tiny child suffers seizures and breathing problems.

Jawdat Al-Bassam, an associate professor of molecular and cellular biology at the University of California, Davis, often hears from these families. “I’ve gotten emails from folks all over the world,” he said.

Plants Walk a Fine Line Between Growth and Defense

Salicylic acid, the active molecule in aspirin and some acne medications, is a hormone in plants that is essential for immunity, but it’s a double-edged sword: too much can cause autoimmunity and stunt growth. In a new study published April 20 in Nature Communications, University of California, Davis, researchers discovered that plants use a surprising multi-layered system to regulate salicylic acid levels and keep their immune system in check.

Fish Evolution Accelerated After Adapting to Eat off Hard Surfaces

Why are there so many species of coral reef fish? According to a new study, it’s because about 50 million years ago, some fish figured out how to bite food from hard surfaces. 

Evolution doesn’t proceed at an even pace—species evolve in jumps and spurts, followed by lulls. These periods of rapid diversification usually occur after a dramatic environmental change or upheaval, or when a lineage develops a new “innovation” that allows them to use a previously inaccessible resource. For fish, the ability to feed from a hard surface was one such innovation.

A Billion Daily Repairs: How Our Cells Mend Broken DNA

A major new discovery could inspire improved treatments for cancer and genetic diseases.

Coiled within our cells are fragile threads of DNA that contain the codes of life— determining when each of our 30 trillion cells must grow, divide, sit tight — or simply die. This arrangement is precarious. Billions of times per day, our DNA is severed by stray chemical reactions. Our cells must rebuild the broken DNA without making mistakes – or the consequences can be dire.

Plant Cell Structure Could Hold Key to Cancer Therapies and Improved Crops

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in human disease. A team led by researchers at the University of California, Davis, has mapped out the structure of a key player, augmin, in exhaustive detail.

Mirror Image Pheromones Help Beetles Swipe Right

There are many ways to communicate with prospective romantic partners: If you are a Japanese scarab beetle, it’s a matter of distinguishing left from right. New work from U.S. and Chinese scientists, published this week in Proceedings of the National Academy of Sciences, shows how these beetles use mirror-image pheromones to find a mate. The work could lead to better monitoring and control of significant agricultural pests.